3D printable Gel-inks for Tissue Engineering Chemistry, Processing, and Applications, Anuj Kumar,Stefan Ioan Voicu,Vijay Kumar Thakur, Editör, Springer, London/Berlin , Dubendorf, ss.161-190, 2021
Corneal transplantation from donor tissue is one of the primary healing
of cornea diseases. However, the scarcity of donor tissue is a serious
problem. Tissue engineering approaches offer an alternative recourse for
corneal regeneration. Corneal tissue engineering (CTE) can provide
tissue substitute to preserve and enhance corneal functions combining
cells, bioactive molecules, and three-dimensional scaffolds for native
cornea transplantation. 3D printing is a novel and rising process for
constructing layer-by-layer fabrication of these materials in clinical
applications. Among the different materials, gel-based inks are
remarkable materials to use as ink in the 3D printing. In view of the
printability feature of the inks, the processing abilities of the
gel-ink formulation is an important parameter to consider. Furthermore,
to produce gel-ink with transparency, non-toxicity, and mechanical
properties almost identical to the human cornea have a vital role in
replacing corneal tissues. Herein, the desired properties for selecting
gel-inks and combination and characterization of inks for 3D printing in
CTE are presented in detail.