Chitosan/Gold Hybrid Nanoparticles Enriched Electrospun PVA Nanofibrous Mats for the Topical Delivery of Punica granatum L. Extract: Synthesis, Characterization, Biocompatibility and Antibacterial Properties

Mohamady Hussein, Mohamed; Ulag, SONGÜL; Abo Dena, Ahmed; Sahin, ALİ; Grinholc, Mariusz; Gunduz, OĞUZHAN; El-Sherbiny, Ibrahim; Megahed, Mosaad

doi:10.2147/ijn.s306526

Chitosan/Gold Hybrid Nanoparticles Enriched Electrospun PVA Nanofibrous Mats for the Topical Delivery of Punica granatum L. Extract: Synthesis, Characterization, Biocompatibility and Antibacterial Properties

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Mohamady Hussein M. A., Ulag S., Abo Dena A. S., Sahin A., Grinholc M., Gunduz O., ...More

INTERNATIONAL JOURNAL OF NANOMEDICINE, vol.16, pp.5133-5151, 2021 (SCI-Expanded)

Publication Type: Article / Article
Volume: 16
Publication Date: 2021
Doi Number: 10.2147/ijn.s306526
Journal Name: INTERNATIONAL JOURNAL OF NANOMEDICINE
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, Biotechnology Research Abstracts, EMBASE, MEDLINE, Directory of Open Access Journals
Page Numbers: pp.5133-5151
Keywords: gold nanoparticles, chitosan, Punica granatum, nanofiber, antibacterial, POLYVINYL-ALCOHOL, POLY(METHYL METHACRYLATE), GOLD NANOPARTICLES, WOUND DRESSINGS, POMEGRANATE, COMPOSITE, DIFFERENTIATION, COMPATIBILITY, PERFORMANCE, VISCOSITY
Marmara University Affiliated: Yes

Abstract

Purpose: Intending to obtain Punica granatum L. extract (PE)-loaded drug delivery system of better impact and biomedical applicability, the current study reports the use of crosslinked PVA nanofibers (NFs) as platforms incorporating different amounts of biosynthesized PE-CS-gold nanoparticles (PE-CS-Au NPs).