Differences in beta-glucan levels in culture supernatants of a variety of fungi

Odabasi Z., Paetznick V. L., Rodriguez J. R., Chen E., McGinnis M. R., Ostrosky-Zeichner L.

MEDICAL MYCOLOGY, cilt.44, sa.3, ss.267-272, 2006 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 44 Sayı: 3
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1080/13693780500474327
  • Dergi Adı: MEDICAL MYCOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.267-272
  • Anahtar Kelimeler: yeast, mould, beta glucan, diagnosis, supernatant, PLASMA, INFECTIONS, DIAGNOSIS, ASPERGILLOSIS, TRICHOSPORON, EPIDEMIOLOGY, LEUKEMIA
  • Marmara Üniversitesi Adresli: Evet

Özet

(1 -> 3)-beta-d-glucan is a well known cell wall constituent of fungal isolates that can be detected by assays in vivo and in vitro. Previous studies have shown that different fungal isolates may show different levels of reactivity with an assay for beta glucan. In this study we evaluated the in vitro reactivity of 127 clinical fungal isolates belonging to 40 different genera, with the Glucatell (TM) assay. The majority of the fungal isolates released high levels of beta glucan. Beta glucan test reactivity appears to be species-specific and this may reflect the beta glucan content of the organism.