Comparison of cooled and uncooled microwave ablation for treating parathyroid adenomas


Paşa O., Taydaş O., Arık E., Topaloğlu Ö. F., Özdemir M., İslam M., ...Daha Fazla

European Conference on Interventional Oncology, Amsterdam, Hollanda, 13 - 16 Nisan 2025, ss.209, (Özet Bildiri)

  • Yayın Türü: Bildiri / Özet Bildiri
  • Basıldığı Şehir: Amsterdam
  • Basıldığı Ülke: Hollanda
  • Sayfa Sayıları: ss.209
  • Marmara Üniversitesi Adresli: Evet

Özet

Purpose:

Percutaneous ablation techniques are often utilized in parathyroid adenoma treatment. This study aimed to

compare the efficacy of cooled versus uncooled microwave ablation (MWA) methods in treating parathyroid

adenomas.

Materials and Methods:

A retrospective analysis was conducted on 40 patients diagnosed with parathyroid adenomas and treated with

ultrasound-guided MWA at our clinic between January 2023 and January 2024. The mean age of the patients

was 54.4 ± 14.6 years, and 67.5% were female. Of the patients, 19 (47.5%) underwent cooled MWA, while 21

(52.5%) received uncooled MWA. Serum PTH and calcium levels were measured and compared at six intervals

before and after the procedure.

Results:

Technical success was 100%. Both groups demonstrated a reduction in PTH and Ca levels over time, although

no statistically significant differences were identified between the two methods. Regarding major

complications, transient hoarseness developed in two patients (5%), one from each group. There was no

significant difference in major complications between the groups (p = 0.879). Minor complications included

persistent pain lasting up to a week after the procedure in one patient (5.3%) in the cooled group and three

patients (14.2%) in the uncooled group, with an overall minor complication rate of 10%. A significant

difference was observed between the groups in minor complications (p = 0.024).

Conclusions:

MWA is effective in treating parathyroid adenomas with both cooled and uncooled methods. However, it is

essential to consider that uncooled MWA may result in higher pain levels during the procedure.