Bacillus Calmette-Guerin, Mycobacterium bovis, as an immunomodulator in atopic diseases


Barlan I., Bahceciler N., Akdis M., Akdis C.

IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA, cilt.26, sa.2, ss.365-378, 2006 (SCI-Expanded) identifier

Özet

Based on the hygiene hypothesis association between atopy and bacillus Calmette-Guerin (BCG), purified protein derivative skin test reaction, mycobacterial disease, and environmental mycobacteria are summarized. The role of mycobacterial species in the activation of the innate immune response through Toll-like receptors is mentioned. The implications and perspectives of BCG as a potential therapeutic adjuvant in atopic disease are discussed.