Bacillus Calmette-Guerin, Mycobacterium bovis, as an immunomodulator in atopic diseases


Barlan I., Bahceciler N., Akdis M., Akdis C.

IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA, cilt.26, sa.2, ss.365-378, 2006 (SCI İndekslerine Giren Dergi) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26 Konu: 2
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1016/j.iac.2006.02.002
  • Dergi Adı: IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA
  • Sayfa Sayıları: ss.365-378

Özet

Based on the hygiene hypothesis association between atopy and bacillus Calmette-Guerin (BCG), purified protein derivative skin test reaction, mycobacterial disease, and environmental mycobacteria are summarized. The role of mycobacterial species in the activation of the innate immune response through Toll-like receptors is mentioned. The implications and perspectives of BCG as a potential therapeutic adjuvant in atopic disease are discussed.