Serum cytokine profiles in Takayasu's arteritis: search for biomarkers

Alibaz-Oner F., Yentur S. P., Saruhan-Direskeneli G., Direskeneli H.

CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, cilt.33, sa.2, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 33 Sayı: 2
  • Basım Tarihi: 2015
  • Dergi Adı: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Takayasu's arteritis, biomarkers, disease activity, GIANT-CELL ARTERITIS, LYMPHOCYTES, DIAGNOSIS, INTERLEUKIN-18, TOCILIZUMAB, RECEPTOR, REVEALS
  • Marmara Üniversitesi Adresli: Evet

Özet

Objective. Assessment of disease activity is one of the major difficulties in patients with Takayasu arteritis (TA) during follow-up. To date, no biomarker is universally accepted to be a surrogate for active disease in TA. In this study, we aimed to investigate levels of various pro-and anti-inflammatory, molecules including serum granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin (IL)-6, IL-8, IL-10, IL-18 and IL-23 in patients with TA.