Serum cytokine profiles in Takayasu's arteritis: search for biomarkers
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, cilt.33, sa.2, 2015 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 33 Sayı: 2
- Basım Tarihi: 2015
- Dergi Adı: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Anahtar Kelimeler: Takayasu's arteritis, biomarkers, disease activity, GIANT-CELL ARTERITIS, LYMPHOCYTES, DIAGNOSIS, INTERLEUKIN-18, TOCILIZUMAB, RECEPTOR, REVEALS
- Marmara Üniversitesi Adresli: Evet
Özet
Objective. Assessment of disease activity is one of the major difficulties in patients with Takayasu arteritis (TA) during follow-up. To date, no biomarker is universally accepted to be a surrogate for active disease in TA. In this study, we aimed to investigate levels of various pro-and anti-inflammatory, molecules including serum granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin (IL)-6, IL-8, IL-10, IL-18 and IL-23 in patients with TA.