The effect of doxazosin and sildenafil citrate combination on bladder tissue contractility, alpha adrenergic receptor, and iNOS subtype expression in a male rat model of partially bladder outlet obstruction

Gumrah, Abdulkadir; TANIDIR, YILÖREN; TİNAY, İLKER; ÖZYÜREK, MUSTAFA; TARCAN, TUFAN

doi:10.1002/nau.23155

The effect of doxazosin and sildenafil citrate combination on bladder tissue contractility, alpha adrenergic receptor, and iNOS subtype expression in a male rat model of partially bladder outlet obstruction

Gumrah A., TANIDIR Y. , TİNAY İ. , ÖZYÜREK M. , TARCAN T.

NEUROUROLOGY AND URODYNAMICS, vol.36, no.6, pp.1479-1487, 2017 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 36 Issue: 6
Publication Date: 2017
Doi Number: 10.1002/nau.23155
Title of Journal : NEUROUROLOGY AND URODYNAMICS
Page Numbers: pp.1479-1487

Abstract

AimsOur aim was to investigate the effects of doxazosin, sildenafil, and their combination on bladder tissue contractility and adrenergic receptor (AR) and inducible nitric oxide synthase (iNOS) expression utilizing a male rat model of partial urethral obstruction (PUO).