Evaluation of the relation between cardiac biomarkers and thorax computerized tomography findings in COVID-19 patients

Ileri C., Dogan Z., ÖZBEN SADIÇ B., Karaoglu C., Gunay N., Tigen K., ...Daha Fazla

BIOMARKERS IN MEDICINE, cilt.15, sa.4, ss.285-293, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 15 Sayı: 4
  • Basım Tarihi: 2021
  • Doi Numarası: 10.2217/bmm-2020-0388
  • Dergi Adı: BIOMARKERS IN MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Chemical Abstracts Core, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.285-293
  • Anahtar Kelimeler: cardiac biomarkers, COVID-19, myocardial injury, thorax CT, troponin, INFECTION
  • Marmara Üniversitesi Adresli: Evet

Özet

Background: Troponin levels may be elevated in COVID-19 infection. The aim of this study was to the explore relation between troponin levels and COVID-19 severity. Materials & methods/Results: One hundred and forty consecutive patients with COVID-19 pneumonia were included. Diagnosis of COVID-19 pneumonia was based on positive chest computed tomography (CT) findings. Quantitative PCR test was performed in all patients. Only 74 patients were quantitative PCR-positive. Twenty four patients had severe CT findings and 27 patients had progressive disease. These patients had significantly lower albumin and higher ferritin, D-dimer, lactate dehydrogenase, C-reactive protein, and high-sensitivity cardiac troponin I (hs-cTnI). Conclusion: COVID-19 patients with severe CT findings and progressive disease had higher hs-cTnI levels suggesting the use of hs-cTnI in risk stratification.