Oxidative DNA damage is significantly correlated with flow-mediated dilation in patients with coronary artery disease

Yurdakul S., ÖZBEN SADIÇ B. , Bilge A. K. , Turkoglu U. M. , Arkaya S., Nisanci Y.

JOURNAL OF INVESTIGATIVE MEDICINE, cilt.56, sa.7, ss.925-930, 2008 (SCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 56 Konu: 7
  • Basım Tarihi: 2008
  • Doi Numarası: 10.2310/jim.0b013e318180a91f
  • Dergi Adı: JOURNAL OF INVESTIGATIVE MEDICINE
  • Sayfa Sayıları: ss.925-930

Özet

Background: Oxidative DNA damage was increased in patients with coronary artery disease (CAD) and correlated with the severity of the disease. Endothelial dysfunction plays a major role in atherosclerotic process. The aim of this study was to explore a relation between oxidative DNA damage and endothelial function in patients with CAD.