Oxidative DNA damage is significantly correlated with flow-mediated dilation in patients with coronary artery disease

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Yurdakul S., ÖZBEN SADIÇ B., Bilge A. K., Turkoglu U. M., Arkaya S., Nisanci Y.

JOURNAL OF INVESTIGATIVE MEDICINE, vol.56, no.7, pp.925-930, 2008 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 56 Issue: 7
• Publication Date: 2008
• Doi Number: 10.2310/jim.0b013e318180a91f
• Journal Name: JOURNAL OF INVESTIGATIVE MEDICINE
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.925-930
• Marmara University Affiliated: Yes

Abstract

Background: Oxidative DNA damage was increased in patients with coronary artery disease (CAD) and correlated with the severity of the disease. Endothelial dysfunction plays a major role in atherosclerotic process. The aim of this study was to explore a relation between oxidative DNA damage and endothelial function in patients with CAD.