Myeloperoxidase and calprotectin; Any role as non-invasive markers for the prediction of inflammation and fibrosis in non-alcoholic steatohepatitis?

Bicakci E., DEMİRTAŞ C. Ö., ÇELİKEL Ç., HAKLAR G., DUMAN D.

TURKISH JOURNAL OF GASTROENTEROLOGY, cilt.31, sa.10, ss.681-687, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31 Sayı: 10
  • Basım Tarihi: 2020
  • Doi Numarası: 10.5152/tjg.2020.19403
  • Dergi Adı: TURKISH JOURNAL OF GASTROENTEROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.681-687
  • Anahtar Kelimeler: Non-alcoholic fatty liver disease, inflammation, fibrosis, oxidative stress, enzyme-linked immunosorbent assay, DISEASE-ACTIVITY, OBESITY, SYSTEM, RISK
  • Marmara Üniversitesi Adresli: Evet

Özet

Background/Aims: Specific serum markers reflecting hepatic inflammation and fibrosis are required to tailor the treatment strategies in non-alcoholic steatohepatitis (NASH). We aimed to investigate the roles of myeloperoxidase (MPO) and calprotectin in predicting the hepatic inflammation status and disease severity in NASH.