Epigenome-Wide Scan Identifies a Treatment-Responsive Pattern of Altered DNA Methylation Among Cytoskeletal Remodeling Genes in Monocytes and CD4+T Cells From Patients With Behcet's Disease

Hughes T., Ture-Ozdemir F., Alibaz-Oner F., Coit P., Direskeneli H., Sawalha A. H.

ARTHRITIS & RHEUMATOLOGY, cilt.66, sa.6, ss.1648-1658, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 66 Sayı: 6
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1002/art.38409
  • Dergi Adı: ARTHRITIS & RHEUMATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1648-1658
  • Marmara Üniversitesi Adresli: Evet

Özet

Objective. The pathogenesis of Behcet's disease (BD), an inflammatory disease with multisystem involvement, remains poorly understood. This study was undertaken to investigate whether there are DNA methylation abnormalities in BD that might contribute to the pathogenesis of the disease.