Dental follicle mesenchymal stem cells regulate responses in sepsis
MARMARA MEDICAL JOURNAL, cilt.33, sa.1, ss.7-16, 2020 (ESCI, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 33 Sayı: 1
- Basım Tarihi: 2020
- Doi Numarası: 10.5472/marumj.681996
- Dergi Adı: MARMARA MEDICAL JOURNAL
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, CINAHL, EMBASE, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.7-16
- Anahtar Kelimeler: Sepsis, Septic shock, Dental follicle mesenchymal stem cells, Immunomodulation, HUMAN BONE-MARROW, INTERFERON-GAMMA, INDUCED IMMUNOSUPPRESSION, MECHANISMS, CYTOKINES
- Marmara Üniversitesi Adresli: Evet
Özet
Objective: Sepsis-induced immune alterations are associated with secondary infections and increased risk of death. The use of mesenchymal stern cells (MSCs) has been described as a novel therapeutic strategy. We evaluated the immunomodulatory effects of human dental follicle (DF-MSCs) on lymphocytes of sepsis and septic shock patients.