Do platelet apoptosis, activation, aggregation, lipid peroxidation and platelet-leukocyte aggregate formation occur simultaneously in hyperlipidemia?

Sener, AZİZE; Ozsavci, DERYA; Oba, R; Demirel, Y; Uras, F; Yardimci, KT

doi:10.1016/j.clinbiochem.2005.09.005

Do platelet apoptosis, activation, aggregation, lipid peroxidation and platelet-leukocyte aggregate formation occur simultaneously in hyperlipidemia?

Sener A., Ozsavci D., Oba R., Demirel Y., Uras F., Yardimci K.

CLINICAL BIOCHEMISTRY, cilt.38, sa.12, ss.1081-1087, 2005 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 38 Sayı: 12
Basım Tarihi: 2005
Doi Numarası: 10.1016/j.clinbiochem.2005.09.005
Dergi Adı: CLINICAL BIOCHEMISTRY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1081-1087
Anahtar Kelimeler: hyperlipidemia, apoptosis, annexin-V, platelet activation, platelet-leukocyte aggregates, platelet MDA, GSH, GpIIb/IIIa, P-selectin, FLOW-CYTOMETRY, FIBRINOGEN BINDING, WHOLE-BLOOD, P-SELECTIN, EXPRESSION, MICROPARTICLES, LIPOPROTEINS, SECRETION, VIVO
Marmara Üniversitesi Adresli: Evet

Özet

Objectives: The circulating lipoproteins may cause some abnormalities in platelet composition and function in hypercholesterolemia. The aim Of this Study was to investigate whether platelet apoptosis, platelet activation, platelet aggregation, platelet-leukocyte aggregate (PLA) formation and lipid peroxidation occur simultaneously in hyperlipidemia.