The impact of major depression on heart rate variability and endothelial dysfunction in patients with stable coronary artery disease

Sunbul E. A., SÜNBÜL M., Gulec H.

GENERAL HOSPITAL PSYCHIATRY, vol.44, pp.4-9, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 44
  • Publication Date: 2017
  • Doi Number: 10.1016/j.genhosppsych.2016.10.006
  • Journal Name: GENERAL HOSPITAL PSYCHIATRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
  • Page Numbers: pp.4-9
  • Keywords: Major depression, Endothelial dysfunction, Heart rate variability, Inflammation, CARDIOVASCULAR EVENTS, MYOCARDIAL-ISCHEMIA, CARDIAC EVENTS, RISK-FACTOR, INFLAMMATION, ANXIETY, STRESS, ATHEROSCLEROSIS, ASSOCIATION, COAGULATION
  • Marmara University Affiliated: Yes

Abstract

Background: Depression is an independent risk factor in cardiovascular diseases. Changes in the cardiac autonomic functions and pro-inflammatory processes are potential biological factors. Endothelial dysfunction plays an important role in the etiopathogenesis of atherosclerosis. Our objective was to evaluate the impact of major depression on heart rate variability and endothelial dysfunction in patients with stable CAD.