The effect of intradetrusor botulinum neurotoxin type A on urinary NGF, TGF BETA-1, TIMP-2 levels in children with neurogenic detrusor overactivity due to myelodysplasia

Top, Tuncay; Sekerci, ÇAĞRI; Isbilen-Basok, Banu; TANIDIR, YILÖREN; TİNAY, İLKER; İŞMAN, FERRUH; Akbal, Cem; ŞİMŞEK, FERRUH; TARCAN, TUFAN

doi:10.1002/nau.23207

The effect of intradetrusor botulinum neurotoxin type A on urinary NGF, TGF BETA-1, TIMP-2 levels in children with neurogenic detrusor overactivity due to myelodysplasia

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Top T., Sekerci Ç. A., Isbilen-Basok B., TANIDIR Y., TİNAY İ., İŞMAN F. K., ...More

NEUROUROLOGY AND URODYNAMICS, vol.36, no.7, pp.1896-1902, 2017 (SCI-Expanded)

Publication Type: Article / Article
Volume: 36 Issue: 7
Publication Date: 2017
Doi Number: 10.1002/nau.23207
Journal Name: NEUROUROLOGY AND URODYNAMICS
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.1896-1902
Keywords: nerve growth factor, transforming growth factor beta 1, tissue inhibitor of matrix metalloproteinase 2, botulinum neurotoxin type A, myelodysplasia, NERVE GROWTH-FACTOR, BLADDER, OBSTRUCTION, INJECTIONS, FIBROSIS, TOXIN, SECONDARY
Marmara University Affiliated: Yes

Abstract

AimsThe aim of this study was to determine the value of urine nerve growth factor (NGF), transforming growth factor beta 1 (TGF-Beta-1), tissue inhibitor of matrix metalloproteinase 2 (TIMP-2) levels to predict the urodynamic profile before and after botulinum neurotoxin type A (BoNT-A) treatment in children with myelodysplasia.