Effect of oxidative stress on aorta and tibia osteoprotegerin gene expression in ovariectomized rats

AYDIN H., DEYNELİ O., YAVUZ D., YÜKSEL M., TARÇIN Ö., YAZICI D., ...Daha Fazla

MINERVA ENDOCRINOLOGICA, cilt.36, sa.2, ss.107-115, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 36 Sayı: 2
  • Basım Tarihi: 2011
  • Dergi Adı: MINERVA ENDOCRINOLOGICA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.107-115
  • Anahtar Kelimeler: Ovariectomy, Osteoprotegerin, Oxidative stress, HORMONE REPLACEMENT THERAPY, BONE-MINERAL DENSITY, KAPPA-B LIGAND, NITRIC-OXIDE, ESTROGEN DEFICIENCY, VASCULAR CALCIFICATION, RECEPTOR ACTIVATOR, ENDOTHELIAL DYSFUNCTION, POSTMENOPAUSAL WOMEN, OSTEOPOROSIS
  • Marmara Üniversitesi Adresli: Evet

Özet

Aim. Atherosclerosis and osteoporosis share some common pathophysiological pathways. Increase in oxidative stress and activation of cytokines that increase osteoclastogenesis were reported in postmenopausal period. The aim of this study was to determine the link between these two states.