Akademik Veri Yönetim Sistemi
Applications of Chemistry in Nanosciences and Biomaterials Engineering NanoBioMat 2024 – Summer Edition, Bucuresti, Romanya, 19 - 21 Haziran 2024, ss.35-36
Throughout history, wound dressings have undergone numerous significant enhancements. Evolution started with the utilization of natural materials for basic wound heeling and progressed to employing innovative techniques that can be tailored to execute various remarkable functions. Conventional wound dressings necessitate frequent replacement, are susceptible to bacterial proliferation, and contribute significantly to environmental pollution. Hence, there's a growing demand for biodegradable and antibacterial dressings. Modern wound dressings, crafted from electrospun polymers, incorporate diverse active compounds, like antimicrobial agents, to facilitate wound healing while safeguarding against dehydration and infection. In this study, Peo/SA fibers were initially prepared via electrospinning, suggesting their potential as materials for wound dressings. Morphology, composition, cytotoxicity, and antibacterial activity of nano fibers were characterized by using Fourier transform infrared spectroscopy, differential scanning calorimetry , Scanning electron microscopy , Rheological testing, Swelling Degradation, Tensile testing, Antimicrobial and Biocompatibility test. The results indicate uniform dispersion of SA particles across Peo fibers' surface, with no observed cytotoxic effects. Moreover, the Peo/SA fibers demonstrate remarkable antibacterial efficacy against both Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli), leading to a substantial decrease in bacterial count. Hence, this biodegradable, non-toxic, and antibacterial fiber holds great promise for applications in wound dressing.