Effect of Smoking on Rat Basilar Artery: Correlation with Inducible Nitric Oxide Synthase and Endothelin Converting Enzyme-1

Koc K., ANIK İ., Bozkurt S., Ercin C., CEYLAN S.

TURKISH NEUROSURGERY, vol.19, no.4, pp.393-399, 2009 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 4
  • Publication Date: 2009
  • Journal Name: TURKISH NEUROSURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.393-399
  • Marmara University Affiliated: Yes

Abstract

AIM: Smoking is an extremely important risk factor for subarachnoid hemorrhage and seems to increase rupture risk of unruptured aneurysms by accelerating their growth rate. The aim of the study was to investigate the effect of smoking on the luminal diameter with wall thicknesses of rat basilar arteries and to detect alterations of inducible nitric oxide synthase and endothelin-converting enzyme -1 in the endothelial cells.