Simultaneous analysis of miRNA-mRNA in human meningiomas by integrating transcriptome: A relationship between PTX3 and miR-29c

Dalan A. B., GÜLLÜOĞLU Ş., Tuysuz E. C., Kuskucu A., Yaltirik C. K., ÖZTÜRK O., ...More

BMC CANCER, vol.17, 2017 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 17
  • Publication Date: 2017
  • Doi Number: 10.1186/s12885-017-3198-4
  • Journal Name: BMC CANCER
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: meningioma, microarray, miRNA, transcriptome, PTX3, miR-29c, GENE-EXPRESSION, ANAPLASTIC MENINGIOMAS, MOLECULAR-GENETICS, CANCER, CLASSIFICATION, PROLIFERATION, INFLAMMATION, CELL
  • Marmara University Affiliated: No

Abstract

Background: Although meningioma is a common disease, there is a lack of understanding of the underlying molecular mechanisms behind its initiation and progression. We used combined miRNA-mRNA transcriptome analysis to discover dysregulated genes and networks in meningiomas.