The relationship between macrolide resistance mechanisms and serotypes of Streptococcus pneumoniae

Tiryakioglu N., AKSU M. B., HASDEMİR GÖKBOĞA M. U.

CLINICAL AND EXPERIMENTAL HEALTH SCIENCES, vol.2, no.3, pp.124-129, 2012 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 2 Issue: 3
  • Publication Date: 2012
  • Journal Name: CLINICAL AND EXPERIMENTAL HEALTH SCIENCES
  • Journal Indexes: Emerging Sources Citation Index (ESCI)
  • Page Numbers: pp.124-129
  • Keywords: Macrolide resistance, erm(B), mef(E), serotype, Streptococcus pneumoniae
  • Marmara University Affiliated: Yes

Abstract

Objective: Increased resistance rate to macrolides used as empirical treatment of pneumococcal infections is a major problem in our country and all over the world. In our study, we aimed to determine macrolide resistance mechanisms of the erythromycin-resistant Streptococcus pneumonia isolated from clinical samples and to investigate serotype and resistance relationship within our region with the high macrolide resistance rates among pneumococci.