GCK gene mutations are a common cause of childhood-onset MODY (maturity-onset diabetes of the young) in Turkey.

Haliloglu B., Hysenaj G., Atay Z., GÜRAN T., Abali S., Turan S., ...More

Clinical endocrinology, vol.85, no.3, pp.393-9, 2016 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 85 Issue: 3
  • Publication Date: 2016
  • Doi Number: 10.1111/cen.13121
  • Journal Name: Clinical endocrinology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.393-9
  • Marmara University Affiliated: Yes

Abstract

ObjectiveInactivating heterozygous mutations in the GCK gene are a common cause of MODY and result in mild fasting hyperglycaemia, which does not require treatment. We aimed to identify the frequency, clinical and molecular features of GCK mutations in a Turkish paediatric cohort.