Cardiovascular rhythms in the 0.15-Hz band: common origin of identical phenomena in man and dog in the reticular formation of the brain stem?

Perlitz V., Lambertz M., Cotuk B. , Grebe R., Vandenhouten R., Flatten G., ...Daha Fazla

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, cilt.448, sa.6, ss.579-591, 2004 (SCI İndekslerine Giren Dergi) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 448 Konu: 6
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1007/s00424-004-1291-4
  • Sayfa Sayıları: ss.579-591


Selected examples from experiments in humans and dogs with time series of reticular neurons, respiration, arterial blood pressure and cutaneous forehead blood content fluctuations were analysed using multiscaled time-frequency distribution, post-event-scan and pointwise transinformation. We found in both experiments a "0.15-Hz rhythm" exhibiting periods of spindle waves (increasing and decreasing amplitudes), phase synchronized with respiration at 1:2 and 1: 1 integer number ratios. At times of wave-epochs and n:m phase synchronization, the 0.15-Hz rhythm appeared in heart rate and arterial blood pressure. As phase synchronization of the 0.15-Hz rhythm with respiration was established at a 1:1 integer number ratio, all cardiovascular-respiratory oscillations were synchronized at 0.15 Hz. Analysis of a canine experiment supplied evidence that the emergence of the 0.15-Hz rhythm and n:m phase synchronization appears to result from a decline in the level of the general activity of the organism associated with a decline in the level of activity of reticular neurons in the lower brainstem network. These findings corroborate the notion of the 0.15-Hz rhythm as a marker of the "trophotropic mode of operation" first introduced by W.R. Hess.