Efficacy of N-acetylcysteine in preventing amphotericin B induced acute kidney injury

ERTÜRK ŞENGEL B., Tukenmez Tigen E., TOPTAŞ T., ATAGÜNDÜZ I., TUĞLULAR A. T., Ergonul M. O., ...Daha Fazla

MARMARA MEDICAL JOURNAL, cilt.29, sa.2, ss.73-78, 2016 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 29 Sayı: 2
  • Basım Tarihi: 2016
  • Doi Numarası: 10.5472/mmjoa.2902.02
  • Dergi Adı: MARMARA MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.73-78
  • Marmara Üniversitesi Adresli: Evet

Özet

Objectives: Previously, in an animal study we showed that N-acetylcysteine (NAC) could decrease deoxycholate amphotericin B (DAmB) induced renal tubular apoptosis. In this clinical study, we aimed to evaluate the efficacy of NAC in preventing acute kidney injury (AKI) in febrile neutropenic patients with invasive pulmonary aspergillosis treated with DAmB.