Circulating Levels of Vascular Endothelial Growth Factor A and Its Soluble Receptor in Patients with Biopsy-proven Nonalcoholic Fatty Liver Disease

Yılmaz Y., Yonal O., Kurt R., Alahdab Y., Ozdogan O., Celikel Ç., ...More

ARCHIVES OF MEDICAL RESEARCH, vol.42, no.1, pp.38-43, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 42 Issue: 1
  • Publication Date: 2011
  • Doi Number: 10.1016/j.arcmed.2010.12.001
  • Journal Name: ARCHIVES OF MEDICAL RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.38-43
  • Keywords: Vascular endothelial growth factor, Nonalcoholic fatty liver disease, Liver fibrosis, Enzyme-linked immunosorbent assay, Steatohepatitis, METABOLIC SYNDROME, PLASMA-LEVELS, VEGF, ANGIOGENESIS, ASSOCIATION, STEATOHEPATITIS, HYPERTENSION, SFLT-1, CELLS, RISK
  • Marmara University Affiliated: Yes

Abstract

Background and Aims. Vascular endothelial growth factor A (VEGF) is a multifunctional cytokine affecting angiogenesis and vascular function. The biological activity of VEGF is modulated by its soluble receptor VEGFR-1 (sVEGFR-1). We explored the associations of VEGF and sVEGFR-1 concentrations with liver histology in patients with biopsy-proven nonalcoholic fatty liver disease (NAFLD).