Periodontitis in Rats Induces Systemic Oxidative Stress That Is Controlled by Bone-Targeted Antiresorptives


Oktay S., Chukkapalli S. S. , Rivera-Kweh M. F. , Velsko I. M. , Holliday L. S. , Kesavalu L.

JOURNAL OF PERIODONTOLOGY, cilt.86, ss.137-145, 2015 (SCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 86 Konu: 1
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1902/jop.2014.140302
  • Dergi Adı: JOURNAL OF PERIODONTOLOGY
  • Sayfa Sayıları: ss.137-145

Özet

Background: Periodontitis is a chronic, polymicrobial inflammatory disease that degrades connective tissue and alveolar bone and results in tooth loss. Oxidative stress has been linked to the onset of periodontal tissue breakdown and systemic inflammation, and the success of antiresorptive treatments will rely on how effectively they can ameliorate periodontal disease-induced oxidative stress during oral infection.