Salivary interleukin-17 and tumor necrosis factor- in relation to periodontitis and glycemic status in type 2 diabetes mellitus

Gursoy U. K., Yildiz Ciftlikli S., Kononen E., Gursoy M., Doğan B.

JOURNAL OF DIABETES, cilt.7, ss.681-688, 2015 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 7
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1111/1753-0407.12228
  • Dergi Adı: JOURNAL OF DIABETES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.681-688
  • Anahtar Kelimeler: interleukin-17, periodontal disease, saliva, tumor necrosis factor-, type 2 diabetes mellitus, MATRIX METALLOPROTEINASES, CYTOKINE LEVELS, IL-17, CELLS, PATHOGENESIS, EXPRESSION
  • Marmara Üniversitesi Adresli: Evet

Özet

BackgroundPoorly-controlled glycemic status in type 2 diabetes mellitus (T2DM) is suggested to play a role in the periodontal inflammatory process by aggregating the local cytokine response. Our objectives were to profile salivary interleukin (IL)-17 and tumor necrosis factor (TNF)- levels in subjects with T2DM and to examine their relevance for the periodontal health status and glycemic control levels.