Biological activities of hydrazone derivatives

Rollas S., Kucukguzel Ş. G.

MOLECULES, cilt.12, sa.8, ss.1910-1939, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 12 Sayı: 8
  • Basım Tarihi: 2007
  • Doi Numarası: 10.3390/12081910
  • Dergi Adı: MOLECULES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1910-1939
  • Anahtar Kelimeler: hydrazones, hydrazide-hydrazones, biological activity, isoniazid, ANTIMICROBIAL ACTIVITY, IN-VITRO, ANTIMYCOBACTERIAL ACTIVITY, PHARMACOLOGICAL EVALUATION, ACYLHYDRAZONE DERIVATIVES, ANTITUBERCULOSIS ACTIVITY, COUPLING PRODUCTS, ACID HYDRAZONES, HYDRAZIDES, RESISTANT
  • Marmara Üniversitesi Adresli: Evet

Özet

There has been considerable interest in the development of novel compounds with anticonvulsant, antidepressant, analgesic, antiinflammatory, antiplatelet, antimalarial, antimicrobial, antimycobacterial, antitumoral, vasodilator, antiviral and antischistosomiasis activities. Hydrazones possessing an azometine -NHN=CH- proton constitute an important class of compounds for new drug development. Therefore, many researchers have synthesized these compounds as target structures and evaluated their biological activities. These observations have been guiding for the development of new hydrazones that possess varied biological activities.