Systematic Review of Central Post Stroke Pain What Is Happening in the Central Nervous System?


Akyuz G., Kuru P.

AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION, cilt.95, sa.8, ss.618-627, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 95 Sayı: 8
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1097/phm.0000000000000542
  • Dergi Adı: AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.618-627
  • Anahtar Kelimeler: Central Pain, Pathophysiology, Stroke, CENTRAL POSTSTROKE PAIN, TRANSCRANIAL MAGNETIC STIMULATION, MOTOR CORTEX STIMULATION, CENTRAL NEUROPATHIC PAIN, RANDOMIZED CONTROLLED-TRIAL, DEEP BRAIN-STIMULATION, SPINAL-CORD-INJURY, ELECTRICAL-STIMULATION, DEAFFERENTATION PAIN, DOUBLE-BLIND
  • Marmara Üniversitesi Adresli: Evet

Özet

Central poststroke pain (CPSP) is one of the most common central neuropathic pain syndromes seen after stroke. It is mainly related with vascular damage at certain brain territory and pain related to corresponding body areas. In the past, it was described as one of the definitive symptoms of thalamic lesion. However, recent findings suggest that it is not only seen after thalamic lesions but also seen after vascular lesions in any part of the central nervous system. Although there are certain hypotheses to explain physiopathologic mechanisms of CPSP, further evidence is needed. The majority of the cases are intractable and unresponsive to analgesic treatment. Electrical stimulation such as deep brain stimulation and repetitive transcranial magnetic stimulation seems to be effective in certain cases. In this systematic review, recent advancements related to CPSP mechanisms have been evaluated. Further investigations are needed in order to reveal the mystery of the pathophysiologic mechanisms of CPSP.