Comparison of the intensity of peripheral inflammation between major depressive disorder and bipolar depression by means of neutrophil-lymphocyte and platelet-lymphocyte ratios: The possible role of clinical severity and psychotic features

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Bulut N. S., YORGUNER N.

MARMARA MEDICAL JOURNAL, cilt.35, sa.1, ss.100-106, 2022 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 35 Sayı: 1
  • Basım Tarihi: 2022
  • Doi Numarası: 10.5472/marumj.1065834
  • Dergi Adı: MARMARA MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, CINAHL, EMBASE, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.100-106
  • Anahtar Kelimeler: Major depressive disorder, Bipolar disorder, Inflammation, Immune dysregulation, Neutrophil-lymphocyte ratio, Platelet-lymphocyte ratio, C-REACTIVE PROTEIN, UNIPOLAR DEPRESSION, NEUTROPHIL/LYMPHOCYTE RATIO, PROINFLAMMATORY MARKERS, SCHIZOPHRENIA, ADIPONECTIN, CYTOKINES, SUBTYPES, STRESS, SYSTEM
  • Marmara Üniversitesi Adresli: Evet

Özet

Objective: The present study aimed to compare the intensity of inflammation between major depressive disorder (MDD) and bipolar disorder-depressive episode (BD-D) by using neutrophil to lymphocyte (NLR) and platelet to lymphocyte ratios (PLR) as nonspecific markers for peripheral immune response, and to investigate whether and how these parameters correlate with the clinical characteristics of the depressive episodes within and between the diagnoses.