MEFV mutations are increased in Behcet's disease (BD) and are associated with vascular involvement

Atagunduz P., Ergun T., Direskeneli H.

CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, cilt.21, sa.4, 2003 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21 Sayı: 4
  • Basım Tarihi: 2003
  • Dergi Adı: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: MEFV, Behcet's disease, vascular complications, FAMILIAL MEDITERRANEAN FEVER, DIAGNOSIS
  • Marmara Üniversitesi Adresli: Evet

Özet

Objective. A high prevalence of Behcet's disease (BD) among familial Mediterranean fever (FMF) patients has been described recently and a weak association of BD and certain MEFV gene mutations, originally linked to FMF has been reported in an ethnically mixed population from France. We further investigated the presence of MEFV mutations in BD patients from Turkey, a country with a high prevalence of both disorders.