Whole Exome Sequencing Identifies Rare Protein-Coding Variants in Behcet's Disease

Ognenovski M., Renauer P., Gensterblum E., Kotter I., Xenitidis T., Henes J. C. , ...Daha Fazla

ARTHRITIS & RHEUMATOLOGY, cilt.68, ss.1272-1280, 2016 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 68 Konu: 5
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1002/art.39545
  • Sayfa Sayıları: ss.1272-1280


Objective. Behcet's disease (BD) is a systemic inflammatory disease with an incompletely understood etiology. Despite the identification of multiple common genetic variants associated with BD, rare genetic variants have been less explored. We undertook this study to investigate the role of rare variants in BD by performing whole exome sequencing in BD patients of European descent.