Akademik Veri Yönetim Sistemi
Biomaterials for Neural Tissue Engineering, Oguzhan Gunduz,Cem Bulent Ustundag,Mustafa Sengor, Editör, Elsevier Science, Oxford/Amsterdam , Oxford, ss.367-415, 2023
The loss of communication between neurons and other cells is the main reason for the failure to regenerate nerve tissue. In recent years, the invention of wonderful biomaterials with the use of tissue engineering and nanotechnology improve treatment options in this field. Nanofibrous, natural and synthetic scaffolds have been developed in order to ensure effective regeneration of the neural damage site. Various cell types such as stem cells, Schwann cells, other peripheral and central nerve systems–related cells have been used to further increase the efficiency of the produced biomaterials. In addition, different types of growth factors were loaded to the scaffolds to induce the differentiation and stimulate the migration of cells to the damage area. In this chapter, we discuss the properties of different biomaterials, their compatibility with different type of cells, and basic techniques used to evaluate in in vitro conditions.