Aplastic Anemia Associated with Oral Terbinafine: A Case Report and Review of the Literature

Kantarcioglu B., TÜRKÖZ H. K., Yilmaz G., Tanrikulu F. P., ATAGÜNDÜZ I., Adiguzel C., ...Daha Fazla

TURKISH JOURNAL OF HEMATOLOGY, cilt.31, sa.4, ss.411-416, 2014 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31 Sayı: 4
  • Basım Tarihi: 2014
  • Doi Numarası: 10.4274/tjh.2013.0119
  • Dergi Adı: TURKISH JOURNAL OF HEMATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.411-416
  • Anahtar Kelimeler: Onychomycosis, Terbinafine, Aplastic anemia, Hematological toxicity, Pancytopenia, Adverse events, RESISTANCE P-GLYCOPROTEIN, POSTMARKETING SURVEILLANCE, AGRANULOCYTOSIS, ONYCHOMYCOSIS, NEUTROPENIA, UPDATE, CELLS
  • Marmara Üniversitesi Adresli: Evet

Özet

Onychomycosis (OM) is a common fungal infection of the toenails and/or fingernails that is highly prevalent in the general population and also responsible for significant morbidity. OM is caused by dermatophytes, nondermatophytic molds, or yeast. Today systemic antifungal agents are considered as the gold standard for all types of OM. Here we report a case of aplastic anemia associated with oral terbinafine use and a review of the literature on hematological toxicities associated with terbinafine.