Mesna (2-mercaptoethane sulfonate) prevents ischemia/reperfusion induced renal oxidative damage in rats

Kabasakal L. , Sehirli A., Cetinel Ş. , Cikler E., Gedik N., Sener G.

LIFE SCIENCES, vol.75, no.19, pp.2329-2340, 2004 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 75 Issue: 19
  • Publication Date: 2004
  • Doi Number: 10.1016/j.lfs.2004.04.029
  • Title of Journal : LIFE SCIENCES
  • Page Numbers: pp.2329-2340


Reoxygenation of the ischemic tissue promotes the generation of various reactive oxygen metabolites (ROM) which are known to have deleterious effects on various cellular functions.