Mycobacterial disease in patients with chronic granulomatous disease: A retrospective analysis of 71 cases


Conti F., Oswaldo Lugo-Reyes S., Blancas Galicia L., He J., AKSU G., de Oliveira E. B. , ...More

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, vol.138, no.1, pp.241-251, 2016 (Journal Indexed in SCI) identifier

  • Publication Type: Article / Article
  • Volume: 138 Issue: 1
  • Publication Date: 2016
  • Doi Number: 10.1016/j.jaci.2015.11.041
  • Title of Journal : JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
  • Page Numbers: pp.241-251

Abstract

Background: Chronic granulomatous disease (CGD) is a rare primary immunodeficiency caused by inborn errors of the phagocyte nicotinamide adenine dinucleotide phosphate oxidase complex. From the first year of life onward, most affected patients display multiple, severe, and recurrent infections caused by bacteria and fungi. Mycobacterial infections have also been reported in some patients.