The effect of some antibiotics on polymorphonuclear leukocyte (PMN) functions and PMN's myeloperoxidase activity, glutathione and malondialdehyde levels of patients with type 2 diabetes mellitus in vitro


RAYAMAN P. , RAYAMAN E. , Cevikbas A., Demirtunc R., Sehirli A. O. , Gurer Ü.

CLINICAL AND EXPERIMENTAL HEALTH SCIENCES, cilt.3, sa.4, ss.200-207, 2013 (ESCI İndekslerine Giren Dergi) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 3 Konu: 4
  • Basım Tarihi: 2013
  • Doi Numarası: 10.5455/musbed.20131215110852
  • Dergi Adı: CLINICAL AND EXPERIMENTAL HEALTH SCIENCES
  • Sayfa Sayıları: ss.200-207

Özet

Objective: In this study, our objective was to compare PMN functions and myeloperoxidase (MPO) activity, glutathione (GSH) and malondialdehyde (MDA) levels and assess the relationship between PMN functions and enzyme levels in patients with type 2 diabetes mellitus (T2DM) and healthy volunteers. We also examined the immunomodulatory effects of ciprofloxacin, rifampicine and doxycycline on PMN functions, MPO activity and GSH and MDA levels.