Serum concentrations of human insulin-like growth factor-1 and levels of insulin-like growth factor-binding protein-5 in patients with nonalcoholic fatty liver disease: association with liver histology

Colak, Yasar; Senates, Ebubekir; Ozturk, Oguzhan; YILMAZ, YUSUF; Zemheri, Ebru; Enc, Feruze; Ulasoglu, Celal; Aksaray, Sebahat; Bozbeyoglu, Sabriye; Kiziltas, Safak; Kurdas, Oya; Tuncer, Ilyas

doi:10.1097/meg.0b013e32834e8041

Serum concentrations of human insulin-like growth factor-1 and levels of insulin-like growth factor-binding protein-5 in patients with nonalcoholic fatty liver disease: association with liver histology

Colak Y., Senates E., Ozturk O., YILMAZ Y., Zemheri E., Enc F. Y., ...Daha Fazla

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, cilt.24, sa.3, ss.255-261, 2012 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 24 Sayı: 3
Basım Tarihi: 2012
Doi Numarası: 10.1097/meg.0b013e32834e8041
Dergi Adı: EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.255-261
Anahtar Kelimeler: fatty liver, insulin-like growth factor-I, insulin-like growth factor binding protein-5, NECROSIS-FACTOR-ALPHA, IGF-I, HEPATOCELLULAR-CARCINOMA, HEPATOCYTE APOPTOSIS, CELLULAR SENESCENCE, PULMONARY-FIBROSIS, METABOLIC SYNDROME, SIMPLE STEATOSIS, STEATOHEPATITIS, POPULATION
Marmara Üniversitesi Adresli: Evet

Özet

Objective In this study, we aimed to investigate the relationship between the histological features of nonalcoholic fatty liver disease (NAFLD) and serum insulin-like growth factor-1 (IGF-1) and insulin-like growth factor-binding protein-5 (IGFBP-5) to determine the usefulness of this relationship in clinical practice.