Medicinal Chemistry and Anti-Inflammatory Activity of Nitric Oxide-Releasing NSAI Drugs


Koc E., KÜÇÜKGÜZEL Ş. G.

MINI-REVIEWS IN MEDICINAL CHEMISTRY, cilt.9, ss.611-619, 2009 (SCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 9 Konu: 5
  • Basım Tarihi: 2009
  • Doi Numarası: 10.2174/138955709788167556
  • Dergi Adı: MINI-REVIEWS IN MEDICINAL CHEMISTRY
  • Sayfa Sayıları: ss.611-619

Özet

Nitric Oxide, which acts as a non-specific cytotoxic mediator and a biological messenger on immunological competence, has been gaining significantly increasing importance. As an alternative to conventional NSAIDs having significant side effects, pharmacologically improved and therapeutically enhanced NO releasing non-steroidal anti-inflammatory drugs with less side effects are being planned to produce.