Synthesis and structure-activity relationships of carbohydrazides and 1,3,4-oxadiazole derivatives bearing an imidazolidine moiety against the yellow fever and dengue vector, Aedes aegypti

TOK F. , Kocyigit-Kaymakcioglu B. , Tabanca N., Estep A. S. , Gross A. D. , Geldenhuys W. J. , ...More

PEST MANAGEMENT SCIENCE, vol.74, no.2, pp.413-421, 2018 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 74 Issue: 2
  • Publication Date: 2018
  • Doi Number: 10.1002/ps.4722
  • Title of Journal : PEST MANAGEMENT SCIENCE
  • Page Numbers: pp.413-421


BACKGROUND 1,3,4-Oxadiazole and imidazolidine rings are important heterocyclic compounds exhibiting a variety of biological activities. In this study, novel compounds with oxadiazole and imidazolidine rings were synthesized from 3-(methylsulfonyl)-2-oxoimidazolidine-1-carbonyl chloride and screened for insecticidal activities. The proposed structures of the 17 synthesized compounds were confirmed using elemental analysis, infrared (IR), proton nuclear magnetic resonance (H-1-NMR), and mass spectroscopy.