Nasal and lower airway level of nitric oxide in children with primary ciliary dyskinesia

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KARADAĞ B. T., James A., Gultekin E., Wilson N., Bush A.

EUROPEAN RESPIRATORY JOURNAL, vol.13, no.6, pp.1402-1405, 1999 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 13 Issue: 6
  • Publication Date: 1999
  • Doi Number: 10.1183/09031936.99.13614069
  • Journal Name: EUROPEAN RESPIRATORY JOURNAL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1402-1405
  • Keywords: child, nitric oxide, primary ciliary dyskinesia, CYSTIC-FIBROSIS, BEAT FREQUENCY, EXHALED AIR
  • Open Archive Collection: AVESIS Open Access Collection
  • Marmara University Affiliated: No

Abstract

Exhaled nitric oxide can be detected in exhaled air and is readily measured by chemiluminescence. It is thought to be involved in both the regulation of ciliary motility and host defence. Recently, upper airway NO has been found to be reduced in a small number of children with primary ciliary dyskinesia (PCD) and its measurement has been recommended as a diagnostic test for this condition.