Functional and structural changes of the urinary bladder following spinal cord injury; treatment with alpha lipoic acid

Ekiz A., ÖZDEMİR KUMRAL Z. N., ERŞAHİN M., Tugtepe H., VELİOĞLU ÖĞÜNÇ A., AKAKIN D., ...Daha Fazla

NEUROUROLOGY AND URODYNAMICS, cilt.36, sa.4, ss.1061-1068, 2017 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 36 Sayı: 4
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1002/nau.23083
  • Dergi Adı: NEUROUROLOGY AND URODYNAMICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1061-1068
  • Anahtar Kelimeler: bladder, carbachol, caspase 3, contractility, lipoic acid, NGF, NSE, papaverinee, relaxation, S100, spinal cord injury, trauma, OXIDATIVE STRESS, DYSFUNCTION, UROTHELIUM, RAT
  • Marmara Üniversitesi Adresli: Evet

Özet

BACKGROUND & AIMAlpha lipoic acid (LA) was shown to exert neuroprotection in trauma-induced spinal cord injury (SCI), which is frequently associated with urinary bladder complaints in patients with SCI. Accordingly, the protective effects of LA on biochemical and histological changes in bladder as well as functional studies were assessed.