Akademik Veri Yönetim Sistemi
Clinical Oral Investigations, cilt.29, sa.5, 2025 (SCI-Expanded)
Objectives: This study aimed to evaluate the clinical success and long-term survival of glass hybrid restorations in permanent first molars affected by molar incisor hypomineralization (MIH) following selective caries removal (SCR) over a six-year follow-up period. Materials and methods: This prospective cohort study included a total of 134 MIH-affected molars in 58 children (mean age 8.94 ± 1.41 years) restored with glass hybrid materials after SCR. Clinical outcomes were assessed at baseline and at 6, 12, 18, 24, and 72 months using modified USPHS criteria. Kaplan-Meier survival analysis and Cox proportional hazards regression with robust standard errors were conducted to evaluate restoration survival and identify potential predictors. Results: The overall estimated mean survival time of restorations was 59.82 ± 1.50 months. The survival probabilities for mild and severe lesions at six-year were 24.3% and 11.1%, respectively. Multivariate Cox proportional hazards regression with robust standard errors indicated that lesion severity, medium lesion extension, and large lesion extension had a statistically significant impact on restoration survival (p < 0.001 for all). While survival was satisfactory up to 2–3 years, a marked decline was observed over time, particularly in severely affected molars. Conclusions: Glass hybrid restorations demonstrated acceptable clinical performance in MIH-affected molars in the short to medium term but showed significant limitations in long-term survival. Clinical relevance: The need for advancements in restorative materials tailored to the structural challenges of MIH. Glass hybrid materials remain a viable option for managing MIH-affected molars, particularly in young patients where minimally invasive approaches are prioritized.