The PREDICT study uncovers three clinical courses of acutely decompensated cirrhosis that have distinct pathophysiology

Trebicka, Jonel; Fernandez, Javier; Papp, Maria; Caraceni, Paolo; Laleman, Wim; Gambino, Carmine; Giovo, Ilaria; Uschner, Frank; Jimenez, Cesar; Mookerjee, Rajeshwar; Gustot, Thierry; Albillos, Agustin; Banares, Rafael; Janicko, Martin; Steib, Christian; Reiberger, Thomas; Acevedo, Juan; Gatti, Pietro; Bernal, William; Zeuzem, Stefan; Zipprich, Alexander; Piano, Salvatore; Berg, Thomas; Bruns, Tony; Bendtsen, Flemming; Coenraad, Minneke; Merli, Manuela; Stauber, Rudolf; Zoller, Heinz; Ramos, Jose; Sole, Cristina; Soriano, German; de Gottardi, Andrea; Gronbaek, Henning; Saliba, Faouzi; Trautwein, Christian; ÖZDOĞAN, OSMAN; Francque, Sven; Ryder, Stephen; Nahon, Pierre; Romero-Gomez, Manuel; Van Vlierberghe, Hans; Francoz, Claire; Manns, Michael; Garcia, Elisabet; Tufoni, Manuel; Amoros, Alex; Pavesi, Marco; Sanchez, Cristina; Curto, Anna; Pitarch, Carla; Putignano, Antonella; Moreno, Esau; Shawcross, Debbie; Aguilar, Ferran; Claria, Joan; Ponzo, Paola; Jansen, Christian; Vitalis, Zsuzsanna; Zaccherini, Giacomo; Balogh, Boglarka; Vargas, Victor; Montagnese, Sara; Alessandria, Carlo; Bernardi, Mauro; Gines, Pere; Jalan, Rajiv; Moreau, Richard; Angeli, Paolo; Arroyo, Vicente

doi:10.1016/j.jhep.2020.06.013

The PREDICT study uncovers three clinical courses of acutely decompensated cirrhosis that have distinct pathophysiology

Atıf İçin Kopyala

Trebicka J., Fernandez J., Papp M., Caraceni P., Laleman W., Gambino C., ...Daha Fazla

JOURNAL OF HEPATOLOGY, cilt.73, ss.842-854, 2020 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 73
Basım Tarihi: 2020
Doi Numarası: 10.1016/j.jhep.2020.06.013
Dergi Adı: JOURNAL OF HEPATOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
Sayfa Sayıları: ss.842-854
Anahtar Kelimeler: Chronic liver disease, Non-elective admission, Acute complications, Outcome, Risk factors, CHRONIC LIVER-FAILURE, INFLAMMATION, MORTALITY, SCORE
Marmara Üniversitesi Adresli: Evet

Özet

Background & Aims: Acute decompensation (AD) of cirrhosis is defined as the acute development of ascites, gastrointestinal hemorrhage, hepatic encephalopathy, infection or any combination thereof, requiring hospitalization. The presence of organ failure(s) in patients with AD defines acute-on-chronic liver failure (ACLF). The PREDICT study is a European, prospective, observational study, designed to characterize the clinical course of AD and to identify predictors of ACLF.