Ga-68-Prostate-Specific Membrane Antigen PET-Positive Paget Bone Disease With Metastatic Prostatic Carcinoma

ENGÜR C. Ö., TUROĞLU H. T., ÖZGÜVEN S., TANIDIR Y., ERDİL T. Y.

CLINICAL NUCLEAR MEDICINE, cilt.45, sa.9, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Editöre Mektup
  • Cilt numarası: 45 Sayı: 9
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1097/rlu.0000000000003198
  • Dergi Adı: CLINICAL NUCLEAR MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Anahtar Kelimeler: Paget disease of bone, Tc-99m-methylene diphosphonate bone scintigraphy, prostate cancer, bone metastases, SPECT-CT (single photon emission computerized tomography/computed tomography), Ga-68-PSMA PET-CT, POTENTIAL-PITFALL, (68)GA-PSMA, FRACTURE, PATIENT
  • Marmara Üniversitesi Adresli: Evet

Özet

Paget bone disease is a chronic benign bone disease characterized by excessive and abnormal bone remodeling. The scintigraphic and bone SPECT/CT hybrid imaging appearances of the affected bone(s) depend on the stage of the disease. We report the case of a patient newly diagnosed with prostate cancer who was found to have multiple osseous metastases, with coexisting Paget disease in the left hemipelvis diagnosed because of typical scintigraphic and SPECT/CT appearance.Ga-68-prostate-specific membrane antigen PET/CT was also performed for initial staging. Pagetoid bones showed increased prostate-specific membrane antigen uptake like skeletal metastases.