Clinical features and management of carboplatin-related hypersensitivity reactions in pediatric low-grade glioma

Genc D. B., Canpolat C., Berrak S. G.

SUPPORTIVE CARE IN CANCER, cilt.20, sa.2, ss.385-393, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20 Sayı: 2
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1007/s00520-011-1123-y
  • Dergi Adı: SUPPORTIVE CARE IN CANCER
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.385-393
  • Anahtar Kelimeler: Carboplatin, Hypersensitivity, Low-grade glioma, Management, PHASE-II, YOUNG-CHILDREN, CHEMOTHERAPY, DESENSITIZATION, EXPERIENCE, TUMORS, RADIOTHERAPY, EVENTS, SAFETY, COMMON
  • Marmara Üniversitesi Adresli: Evet

Özet

The effectiveness of carboplatin and vincristine chemotherapy in the treatment of low-grade glioma (LGG) is well established. However, carboplatin hypersensitivity reactions (CHR) are a major problem leading to premature cessation of therapy. We aimed to investigate the clinical features and the management strategies in CHR, retrospectively.