Molecular Mechanism and Targets of the Antimicrobial Activity of Metal Nanoparticles


OKTAR F. N. , YETMEZ M., Ficai D., Ficai A., Dumitru F., Pica A.

CURRENT TOPICS IN MEDICINAL CHEMISTRY, cilt.15, ss.1583-1588, 2015 (SCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 15 Konu: 16
  • Basım Tarihi: 2015
  • Dergi Adı: CURRENT TOPICS IN MEDICINAL CHEMISTRY
  • Sayfa Sayısı: ss.1583-1588

Özet

The emergence of multi-resistant bacteria to drugs is recognized as a major cause of the increasing number of deaths in hospitals. Killing these bacteria require multiple expensive drugs that can have side effects. Metal nanoparticles may provide a new strategy to combat them. Due the antimicrobial and antiviral properties, nanoparticles (NPs) have outstanding biological properties that can be handled properly for desired applications. This review presents antibacterial and antiviral activity of metal NPs, including the molecular mechanisms by which NPs annihilate multidrug-resistant bacteria.