The effects of desensitizing agents on dentin permeability using a hydraulic conductance device
Dental Materials Journal, cilt.45, sa.5, ss.659-667, 2026 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 45 Sayı: 5
- Basım Tarihi: 2026
- Doi Numarası: 10.4012/dmj.2026-016
- Dergi Adı: Dental Materials Journal
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Compendex, MEDLINE, Health Research Premium Collection (ProQuest)
- Sayfa Sayıları: ss.659-667
- Anahtar Kelimeler: Dentin hypersensitivity, Dentin permeability, Dentinal fluid flow, Desensitizing agents, Hydraulic conductance
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Marmara Üniversitesi Adresli: Evet
Özet
This in vitro study evaluated the effects of a sodium-fluoride varnish, two surface pre-reacted glass-ionomer (S-PRG)-containing agents, and an experimental glycerol-stabilized calcium phosphate cluster (GCPC) gel on dentin permeability using a custom hydraulic conductance apparatus. Horizontal 1-mm coronal dentin disks were prepared from extracted human molars, conditioned with 2% citric acid, and randomized to ClinPro Fluoride Treatment, PRG Barrier-Coat, PRG Pro-Care Gel, experimental GCPC gel, or distilled-water control (n=10/group). Hydraulic conductance was calculated at 3 psi from the time required for 50 μL of water to pass through each specimen. ClinPro and PRG Barrier-Coat significantly reduced permeability after the first post-treatment evaluation, whereas ClinPro and both PRG agents produced near-zero values after the second evaluation. GCPC yielded a moderate but significant reduction. Scanning electron microscopy findings were consistent with progressive dentinal tubule occlusion.