Does Transfusion of Blood and Blood Products Increase the Length of Stay in Hospital?

SARAÇOĞLU A. , Ezelsoy M., Saracoglu K. T.

INDIAN JOURNAL OF HEMATOLOGY AND BLOOD TRANSFUSION, vol.35, no.2, pp.313-320, 2019 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 35 Issue: 2
  • Publication Date: 2019
  • Doi Number: 10.1007/s12288-018-1039-5
  • Page Numbers: pp.313-320
  • Keywords: Blood transfusion, Length of hospital stay, Cardiac surgery, Complication, CARE-UNIT STAY, CARDIAC-SURGERY, CELL TRANSFUSION, BYPASS, GUIDELINES, MORBIDITY, TRIAL


We aimed to analyze the use of blood products in cardiac surgery and to investigate its effect on clinical outcomes. Perioperative transfusion requirement, survival and complication rates and the duration of hospitalization were noted. Patients were divided into two groups considering the duration of hospital and intensive care unit (ICU) stay. The cardiopulmonary bypass time and the cross clamp time, and the amount of used cryoprecipitate, fresh frozen plasma, platelet, red blood cell and the bleeding amount were significantly higher in groups that stayed at the hospital for >7days and at the ICU for >2days (p>0.05). In the univariate model, to predict the patients who might stay at the hospital for more than 1week and who might stay at the ICU for more than 3days, we considered the significant efficacy of postoperative blood transfusion, bleeding amount, and the cardiopulmonary bypass time (p<0.05). In the reduced multivariate model, however, we analyzed the significant-independent efficacy of the postoperative fresh frozen plasma use to determine the patients who would stay at the hospital for more than 1week and who would stay at the ICU for more than 3days (p<0.05). We have concluded that increased use of blood products was associated with the cross clamp and cardiopulmonary bypass time and prolonged duration of hospital and ICU stays. In open cardiac surgeries, the use of blood products due to bleeding was identified as a predictor for staying longer than 3days at the ICU and longer than 7days at the hospital.