Research Information System
AÇBİD 14. International online congress, Antalya, Turkey, 7 - 09 May 2021, pp.17-18, (Summary Text)
Adenomatoid Odontogenic Tumor Arising From a Dentigerous Cyst
Adenomatoid Odontogenic Tumor (AOT) is an uncommon lesion which develops from the
odontogenic epithelium and accounts only 2-7% of all odontogenic tumors. More than two-thirds
of all cases are diagnosed in the second decade of life with a female predominance. It is most
commonly located at the anterior maxilla and generally associated with an impacted tooth, mostly
maxillary canine. Only few cases of AOT associated with a dentigerous cyst have been reported.
In this clinical study an AOT case arising from a dentigerous cyst around the crown of
an unerupted upper first premolar of a 9 year-old girl will be presented. Her clinical
examination revealed an expansion of the cortical bone adjacent to the lesion located at the left maxilla. Radiographically 3 displaced permanent teeth-canine and two premolarswere
detected within the lesion with the largest diameter of 3.2 cm. Histopathological
examination showed an epithelium rich from collagen fibers and stratified squamous cell
layer. Also some parts of it presented adenomatoid lobules and cells similar to ameloblasts.
Histologically, AOT is composed of odontogenic epithelium which may sometimes transfer into
odontogenic neoplasm like ameloblastoma. Therefore some authors classified AOT as a benign
neoplasm, whereas others as developmental hamartoma. The World Health Organization
classified AOT as an epithelial odontogenic tumor which grows slowly but progressively with
almost no symptoms. Thus it is often detected in a routine radiographic examination. However;
in case it is intraosseous, it may present cortical expansion and facial asymmetry.