Melatonin protects against oxidative organ injury in a rat model of sepsis

Sener G., Toklu H., Kapucu C., Ercan F., Erkanli G., Kacmaz A., ...Daha Fazla

SURGERY TODAY, cilt.35, sa.1, ss.52-59, 2005 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 35 Sayı: 1
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1007/s00595-004-2879-1
  • Dergi Adı: SURGERY TODAY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.52-59
  • Anahtar Kelimeler: sepsis, melatonin, lipid peroxidation, glutathione, myeloperoxidase activity, ISCHEMIA-REPERFUSION, FREE-RADICALS, NITRIC-OXIDE, INFLAMMATION, GLUTATHIONE, DAMAGE, MYELOPEROXIDASE, ENDOTHELIUM, PERITONITIS, DYSFUNCTION
  • Marmara Üniversitesi Adresli: Evet

Özet

Purpose. Based on the potent antioxidant effects of melatonin, we investigated the putative protective role of melatonin against sepsis-induced oxidative organ damage in rats.